FOX_gene Fox_ID drug_target drug_taget_ID drug_name pathway target_cor target_pvalue drug_cor drug_pvalue FOXA1 ENSG00000129514 FGFR1 ENSG00000077782 AZD4547 RTK signaling -0.241733414 5.30E-15 0.227342018 3.00E-12 FOXA1 ENSG00000129514 FGFR3 ENSG00000068078 AZD4547 RTK signaling 0.279759439 9.26E-20 0.227342018 3.00E-12 FOXA1 ENSG00000129514 GSK3B ENSG00000082701 CHIR-99021 WNT signaling 0.201631675 8.46E-11 0.267306935 4.27E-30 FOXA1 ENSG00000129514 FGFR1 ENSG00000077782 Foretinib RTK signaling -0.241733414 5.30E-15 0.249001888 4.51E-14 FOXA1 ENSG00000129514 PDGFRB ENSG00000113721 Masitinib RTK signaling -0.29552875 5.77E-22 0.20537805 5.58E-10 FOXA1 ENSG00000129514 CAPN1 ENSG00000014216 MG-132 Protein stability and degradation 0.253666171 2.06E-16 0.209953465 3.14E-05 FOXA1 ENSG00000129514 FGFR1 ENSG00000077782 Ponatinib kinases -0.241733414 5.30E-15 0.254007561 3.82E-14 FOXA1 ENSG00000129514 FGFR1 ENSG00000077782 Ponatinib Other -0.241733414 5.30E-15 0.254007561 3.82E-14 FOXA1 ENSG00000129514 SRC ENSG00000197122 Ponatinib Other 0.240448743 7.44E-15 0.254007561 3.82E-14 FOXA1 ENSG00000129514 SRC ENSG00000197122 Ponatinib kinases 0.240448743 7.44E-15 0.254007561 3.82E-14 FOXA1 ENSG00000129514 DDR1 ENSG00000204580 QL-XI-92 Cytoskeleton 0.476001833 1.08E-58 0.23274685 1.74E-12 FOXA1 ENSG00000129514 GSK3B ENSG00000082701 SB216763 WNT signaling 0.201631675 8.46E-11 0.220242432 1.28E-10 FOXC1 ENSG00000054598 HDAC6 ENSG00000094631 ACY-1215 Chromatin histone acetylation -0.226391309 2.68E-13 0.298276146 6.26E-20 FOXC1 ENSG00000054598 FLT3 ENSG00000122025 Amuvatinib RTK signaling -0.211686164 8.90E-12 0.262849606 1.57E-15 FOXC1 ENSG00000054598 PDK1 ENSG00000152256 BX-912 Metabolism -0.244033172 2.87E-15 0.291887617 4.67E-19 FOXC1 ENSG00000054598 HDAC6 ENSG00000094631 CAY10603 Chromatin histone acetylation -0.226391309 2.68E-13 0.276121558 5.73E-17 FOXC1 ENSG00000054598 EGFR ENSG00000146648 Cetuximab EGFR signaling 0.415940931 7.38E-44 -0.216443155 1.45E-10 FOXC1 ENSG00000054598 ATM ENSG00000149311 CP466722 Genome integrity -0.243769731 3.08E-15 0.232585528 1.75E-12 FOXC1 ENSG00000054598 EGFR ENSG00000146648 CUDC-101 Other 0.415940931 7.38E-44 0.221957456 3.15E-11 FOXC1 ENSG00000054598 SRC ENSG00000197122 Dasatinib Other 0.241278017 5.98E-15 -0.221651898 1.26E-05 FOXC1 ENSG00000054598 SRC ENSG00000197122 Dasatinib kinases 0.241278017 5.98E-15 -0.221651898 1.26E-05 FOXC1 ENSG00000054598 SRC ENSG00000197122 Dasatinib RTK signaling 0.241278017 5.98E-15 -0.221651898 1.26E-05 FOXC1 ENSG00000054598 ROCK1 ENSG00000067900 GSK429286A Cytoskeleton -0.269922822 1.87E-18 0.258419773 4.17E-15 FOXC1 ENSG00000054598 LCK ENSG00000182866 JW-7-24-1 Other -0.276202148 2.78E-19 0.277355818 2.63E-17 FOXC1 ENSG00000054598 LCK ENSG00000182866 JW-7-24-1 kinases -0.276202148 2.78E-19 0.277355818 2.63E-17 FOXC1 ENSG00000054598 PDK1 ENSG00000152256 KIN001-244 Metabolism -0.244033172 2.87E-15 0.2819222 8.51E-18 FOXC1 ENSG00000054598 BCL2 ENSG00000171791 Navitoclax Apoptosis regulation -0.404741334 2.08E-41 0.297407771 2.63E-20 FOXC1 ENSG00000054598 MAP4K2 ENSG00000168067 NG-25 Other -0.211557429 9.17E-12 0.276622909 3.48E-17 FOXC1 ENSG00000054598 MAP4K2 ENSG00000168067 NG-25 kinases -0.211557429 9.17E-12 0.276622909 3.48E-17 FOXC1 ENSG00000054598 PARP1 ENSG00000143799 Olaparib Genome integrity -0.358788332 2.75E-32 0.205685191 2.65E-10 FOXC1 ENSG00000054598 TYMS ENSG00000176890 Pemetrexed DNA replication -0.215688253 3.52E-12 0.261423308 2.90E-15 FOXC1 ENSG00000054598 PIK3CG ENSG00000105851 PIK-93 PI3K/MTOR signaling -0.373580217 4.58E-35 0.319241051 1.32E-22 FOXC1 ENSG00000054598 BTK ENSG00000010671 QL-X-138 Other -0.355445566 1.11E-31 0.243453348 2.09E-13 FOXC1 ENSG00000054598 BTK ENSG00000010671 QL-X-138 kinases -0.355445566 1.11E-31 0.243453348 2.09E-13 FOXC1 ENSG00000054598 DDR1 ENSG00000204580 QL-XI-92 Cytoskeleton 0.40690947 7.10E-42 0.304405993 1.15E-20 FOXC1 ENSG00000054598 FLT3 ENSG00000122025 Quizartinib RTK signaling -0.211686164 8.90E-12 0.306573897 5.94E-21 FOXC1 ENSG00000054598 SIRT1 ENSG00000096717 Selisistat Chromatin histone acetylation -0.203817419 5.24E-11 0.221679707 2.16E-11 FOXC1 ENSG00000054598 DOT1L ENSG00000104885 SGC0946 Chromatin histone methylation -0.34537964 6.81E-30 0.207078459 4.37E-10 FOXC1 ENSG00000054598 MET ENSG00000105976 SU11274 RTK signaling 0.389349558 3.44E-38 0.250958399 2.09E-14 FOXC1 ENSG00000054598 HDAC6 ENSG00000094631 Tubastatin A Chromatin histone acetylation -0.226391309 2.68E-13 0.331196612 2.65E-24 FOXC1 ENSG00000054598 SRC ENSG00000197122 WZ3105 Other 0.241278017 5.98E-15 0.252735366 1.60E-14 FOXC1 ENSG00000054598 FLT3 ENSG00000122025 WZ3105 Other -0.211686164 8.90E-12 0.252735366 1.60E-14 FOXC1 ENSG00000054598 RIPK1 ENSG00000137275 XMD13-2 Apoptosis regulation 0.204970638 4.06E-11 0.290553819 6.85E-19 FOXC1 ENSG00000054598 PIKFYVE ENSG00000115020 YM201636 PI3K/MTOR signaling -0.325525391 1.48E-26 0.270430229 1.90E-16 FOXD4 ENSG00000170122 PIK3CG ENSG00000105851 PIK-93 PI3K/MTOR signaling 0.224382234 4.39E-13 -0.213509131 1.15E-10 FOXE1 ENSG00000178919 EGFR ENSG00000146648 Afatinib EGFR signaling 0.393035618 6.04E-39 -0.220867288 1.51E-21 FOXE1 ENSG00000178919 EGFR ENSG00000146648 Cetuximab EGFR signaling 0.393035618 6.04E-39 -0.216735093 1.37E-10 FOXE1 ENSG00000178919 EGFR ENSG00000146648 Erlotinib EGFR signaling 0.393035618 6.04E-39 -0.258391476 2.93E-07 FOXE1 ENSG00000178919 EGFR ENSG00000146648 Gefitinib EGFR signaling 0.393035618 6.04E-39 -0.263154327 4.54E-16 FOXE1 ENSG00000178919 EGFR ENSG00000146648 Lapatinib EGFR signaling 0.393035618 6.04E-39 -0.256901865 3.33E-07 FOXE1 ENSG00000178919 EGFR ENSG00000146648 Lapatinib RTK signaling 0.393035618 6.04E-39 -0.256901865 3.33E-07 FOXF2 ENSG00000137273 HDAC6 ENSG00000094631 ACY-1215 Chromatin histone acetylation -0.201017243 9.67E-11 0.243942649 1.20E-13 FOXF2 ENSG00000137273 HDAC6 ENSG00000094631 CAY10603 Chromatin histone acetylation -0.201017243 9.67E-11 0.215682143 8.73E-11 FOXF2 ENSG00000137273 HDAC6 ENSG00000094631 Tubastatin A Chromatin histone acetylation -0.201017243 9.67E-11 0.224053598 1.27E-11 FOXJ3 ENSG00000198815 FYN ENSG00000010810 A-770041 Other 0.285132463 1.70E-20 0.222906756 9.83E-06 FOXJ3 ENSG00000198815 FYN ENSG00000010810 A-770041 kinases 0.285132463 1.70E-20 0.222906756 9.83E-06 FOXJ3 ENSG00000198815 HDAC6 ENSG00000094631 ACY-1215 Chromatin histone acetylation 0.201326795 9.04E-11 -0.218279628 3.70E-11 FOXJ3 ENSG00000198815 KIT ENSG00000157404 Dasatinib Other 0.260291661 3.16E-17 0.244299912 1.39E-06 FOXJ3 ENSG00000198815 KIT ENSG00000157404 Dasatinib kinases 0.260291661 3.16E-17 0.244299912 1.39E-06 FOXJ3 ENSG00000198815 KIT ENSG00000157404 Dasatinib RTK signaling 0.260291661 3.16E-17 0.244299912 1.39E-06 FOXJ3 ENSG00000198815 HDAC6 ENSG00000094631 Tubastatin A Chromatin histone acetylation 0.201326795 9.04E-11 -0.215985258 6.92E-11 FOXK2 ENSG00000141568 HDAC6 ENSG00000094631 ACY-1215 Chromatin histone acetylation 0.209847573 1.36E-11 -0.227637614 4.96E-12 FOXN2 ENSG00000170802 EGFR ENSG00000146648 Lapatinib RTK signaling -0.289102318 4.75E-21 0.257719501 3.05E-07 FOXN2 ENSG00000170802 EGFR ENSG00000146648 Lapatinib EGFR signaling -0.289102318 4.75E-21 0.257719501 3.05E-07 FOXN3 ENSG00000053254 ROCK1 ENSG00000067900 GSK429286A Cytoskeleton 0.289513121 4.16E-21 -0.235206982 1.06E-12 FOXN3 ENSG00000053254 BRD3 ENSG00000169925 I-BET-762 Chromatin other 0.240137296 8.08E-15 -0.271391811 1.59E-16 FOXN3 ENSG00000053254 BRD4 ENSG00000141867 I-BET-762 Chromatin other 0.253879328 1.94E-16 -0.271391811 1.59E-16 FOXN3 ENSG00000053254 LCK ENSG00000182866 JW-7-24-1 Other 0.238196042 1.34E-14 -0.220963708 2.21E-11 FOXN3 ENSG00000053254 LCK ENSG00000182866 JW-7-24-1 kinases 0.238196042 1.34E-14 -0.220963708 2.21E-11 FOXN3 ENSG00000053254 FLT3 ENSG00000122025 Linifanib RTK signaling 0.209470672 1.48E-11 -0.20549352 5.34E-10 FOXN3 ENSG00000053254 BCL2 ENSG00000171791 Navitoclax Apoptosis regulation 0.395893522 1.55E-39 -0.293553452 8.41E-20 FOXN3 ENSG00000053254 CLK4 ENSG00000113240 PI-103 Other 0.244839105 2.32E-15 -0.209786186 3.00E-10 FOXN3 ENSG00000053254 CLK4 ENSG00000113240 PI-103 kinases 0.244839105 2.32E-15 -0.209786186 3.00E-10 FOXN3 ENSG00000053254 DDR1 ENSG00000204580 QL-XI-92 Cytoskeleton -0.378153804 5.92E-36 -0.252314356 1.77E-14 FOXN3 ENSG00000053254 BTK ENSG00000010671 QL-XII-61 Other 0.322148957 5.17E-26 -0.229272749 6.68E-07 FOXN3 ENSG00000053254 BTK ENSG00000010671 QL-XII-61 kinases 0.322148957 5.17E-26 -0.229272749 6.68E-07 FOXN3 ENSG00000053254 FLT3 ENSG00000122025 Quizartinib RTK signaling 0.209470672 1.48E-11 -0.277455851 2.67E-17 FOXN3 ENSG00000053254 HDAC6 ENSG00000094631 Tubastatin A Chromatin histone acetylation 0.23992961 8.53E-15 -0.253226322 1.56E-14 FOXN4 ENSG00000139445 FYN ENSG00000010810 A-770041 Other 0.262147321 1.85E-17 0.201610094 6.63E-05 FOXN4 ENSG00000139445 FYN ENSG00000010810 A-770041 kinases 0.262147321 1.85E-17 0.201610094 6.63E-05 FOXN4 ENSG00000139445 HDAC6 ENSG00000094631 ACY-1215 Chromatin histone acetylation 0.264498755 9.32E-18 -0.218706187 3.38E-11 FOXN4 ENSG00000139445 KIT ENSG00000157404 Dasatinib Other 0.264921963 8.23E-18 0.247870249 9.63E-07 FOXN4 ENSG00000139445 KIT ENSG00000157404 Dasatinib kinases 0.264921963 8.23E-18 0.247870249 9.63E-07 FOXN4 ENSG00000139445 KIT ENSG00000157404 Dasatinib RTK signaling 0.264921963 8.23E-18 0.247870249 9.63E-07 FOXQ1 ENSG00000164379 HDAC6 ENSG00000094631 ACY-1215 Chromatin histone acetylation -0.227244202 2.17E-13 0.268243133 2.79E-16 FOXQ1 ENSG00000164379 HDAC6 ENSG00000094631 CAY10603 Chromatin histone acetylation -0.227244202 2.17E-13 0.221700995 2.51E-11 FOXQ1 ENSG00000164379 EGFR ENSG00000146648 Cetuximab EGFR signaling 0.424000419 1.11E-45 -0.205809523 1.14E-09 FOXQ1 ENSG00000164379 EGFR ENSG00000146648 Erlotinib EGFR signaling 0.424000419 1.11E-45 -0.223423669 1.01E-05 FOXQ1 ENSG00000164379 ROCK1 ENSG00000067900 GSK269962A Cytoskeleton -0.213951187 5.27E-12 0.228073225 1.04E-16 FOXQ1 ENSG00000164379 PDK1 ENSG00000152256 KIN001-244 Metabolism -0.265850872 6.27E-18 0.219508827 3.24E-11 FOXQ1 ENSG00000164379 ERBB2 ENSG00000141736 Lapatinib EGFR signaling 0.24322108 3.57E-15 -0.279211637 2.63E-08 FOXQ1 ENSG00000164379 ERBB2 ENSG00000141736 Lapatinib RTK signaling 0.24322108 3.57E-15 -0.279211637 2.63E-08 FOXQ1 ENSG00000164379 EGFR ENSG00000146648 Lapatinib RTK signaling 0.424000419 1.11E-45 -0.279211637 2.63E-08 FOXQ1 ENSG00000164379 EGFR ENSG00000146648 Lapatinib EGFR signaling 0.424000419 1.11E-45 -0.279211637 2.63E-08 FOXQ1 ENSG00000164379 MDM4 ENSG00000198625 NSC-207895 p53 pathway -0.330092246 2.65E-27 0.233165769 1.82E-12 FOXQ1 ENSG00000164379 PARP1 ENSG00000143799 Olaparib Genome integrity -0.402335128 6.81E-41 0.213813324 4.91E-11 FOXQ1 ENSG00000164379 BTK ENSG00000010671 QL-X-138 Other -0.232724519 5.49E-14 0.216358635 7.79E-11 FOXQ1 ENSG00000164379 BTK ENSG00000010671 QL-X-138 kinases -0.232724519 5.49E-14 0.216358635 7.79E-11 FOXQ1 ENSG00000164379 DDR1 ENSG00000204580 QL-XI-92 Cytoskeleton 0.491462693 5.16E-63 0.265301804 6.73E-16 FOXQ1 ENSG00000164379 MET ENSG00000105976 SU11274 RTK signaling 0.404716834 2.11E-41 0.223208005 1.23E-11 FOXQ1 ENSG00000164379 HDAC6 ENSG00000094631 Tubastatin A Chromatin histone acetylation -0.227244202 2.17E-13 0.273644878 8.41E-17 FOXQ1 ENSG00000164379 BCL2 ENSG00000171791 TW 37 Apoptosis regulation -0.299309829 1.63E-22 0.211834917 8.37E-11 FOXQ1 ENSG00000164379 PIKFYVE ENSG00000115020 YM201636 PI3K/MTOR signaling -0.320932393 8.08E-26 0.20623361 4.82E-10