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Drugs And Genes
DRUGs and GENEs
GENE_SYMBOL HGNC_ID UNIPROT_ID DRUG_NAME PUBCHEM_CID Datasource
TOP1 HGNC:11986 P11387 (7E)-4-ethyl-4-hydroxy-7-(2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione 10000564 TTD
TOP1 HGNC:11986 P11387 19-Ethyl-7-fluoro-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-10-carboxylic acid 10001587 TTD
TOP1 HGNC:11986 P11387 tert-butyl N-[[(19S)-19-ethyl-19-hydroxy-10-methyl-6-oxido-14,18-dioxo-17-oxa-3,13-diaza-6-azoniapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl]methyl]carbamate 10006466 TTD
TOP1 HGNC:11986 P11387 (5S)-5-ethyl-5-hydroxy-7,20-dioxa-11,18,24-triazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(13),2,4(9),14,16,18,21,23-octaene-6,10-dione 10023217 TTD
TOP1 HGNC:11986 P11387 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-13-(1,3-dihydroxypropan-2-ylamino)-6,20-dihydroxy-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione 10053929 TTD
TOP1 HGNC:11986 P11387 4-Furan-2-yl-2-((E)-2-furan-2-yl-vinyl)-6-thiophen-2-yl-pyridine 10064551 TTD
TOP1 HGNC:11986 P11387 (4R,7E)-4-ethyl-4-hydroxy-7-(2-oxo-1H-indol-3-ylidene)-1,8-dihydropyrano[3,4-f]indolizine-3,6,10-trione 10091894 TTD
TOP1 HGNC:11986 P11387 (19S)-7-(aminomethyl)-10,19-diethyl-19-hydroxy-17-oxa-3,6,13-triazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione 10092735 TTD
TOP1 HGNC:11986 P11387 (18S)-18-ethyl-18-hydroxy-2-(pyrazin-1-ium-1-ylmethyl)-6,9,20-trioxa-13,24-diazahexacyclo[12.11.0.03,12.05,10.015,24.017,22]pentacosa-1,3,5(10),11,13,15,17(22)-heptaene-19,23-dione 10097407 TTD
TOP1 HGNC:11986 P11387 N-[4-(3,4-dihydroxy-benzoylamino)-phenyl]-3,4-dihydroxy-benzamide 10110293 TTD
TOP1 HGNC:11986 P11387 (19S)-19-ethyl-19-hydroxy-8-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione 10133241 TTD
TOP1 HGNC:11986 P11387 10-Chlorocamptothecin 10156768 TTD
TOP1 HGNC:11986 P11387 N-[2-(3,4-dihydroxy-benzoylamino)-phenyl]-3,4-dihydroxy-benzamide 10177790 TTD
TOP1 HGNC:11986 P11387 (19S)-7-(3-aminoprop-1-ynyl)-10,19-diethyl-19-hydroxy-17-oxa-3,6,13-triazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione 10252111 TTD
TOP1 HGNC:11986 P11387 (19S)-8-chloro-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione 10271273 TTD
TOP1 HGNC:11986 P11387 (19S)-19-ethyl-19-hydroxy-7-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione 10292113 TTD
TOP1 HGNC:11986 P11387 (19S)-8-ethenyl-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione 10317270 TTD
TOP1 HGNC:11986 P11387 (19S)-7-(aminomethyl)-19-ethyl-19-hydroxy-10-methyl-6-oxido-17-oxa-3,13-diaza-6-azoniapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione 10319267 TTD
TOP1 HGNC:11986 P11387 (19S)-7-[3-(dimethylamino)prop-1-ynyl]-10,19-diethyl-19-hydroxy-17-oxa-3,6,13-triazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione 10321913 TTD
TOP1 HGNC:11986 P11387 (19S)-N-[2-(dimethylamino)ethyl]-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,6,13-triazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-7-carboxamide 10323343 TTD