| PATHWAY_NAME |
REACTOME_ID |
KEGG_ID |
DRUG_NAME |
PUBCHEM_CID |
Datasource |
| Acute myeloid leukemia |
R-HSA-9680350 |
map05221 |
Ponatinib |
24826799 |
pubchem |
| Acute myeloid leukemia |
R-HSA-9680350 |
map05221 |
Quizartinib |
24889392 |
pubchem |
| Disease |
R-HSA-1643685 |
0 |
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine |
68911 |
pubchem |
| Diseases of signal transduction by growth factor receptors and second messengers |
0 |
0 |
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine |
68911 |
pubchem |
| Signaling by ALK in cancer |
R-HSA-9700206 |
0 |
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine |
68911 |
pubchem |
| Drug resistance of ALK mutants |
R-HSA-9700649 |
0 |
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine |
68911 |
pubchem |
| ASP-3026-resistant ALK mutants |
R-HSA-9717264 |
0 |
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine |
68911 |
pubchem |
| Disease |
R-HSA-1643685 |
0 |
Pexidartinib |
25151352 |
pubchem |
| Diseases of signal transduction by growth factor receptors and second messengers |
0 |
0 |
Pexidartinib |
25151352 |
pubchem |
| FLT3 signaling in disease |
R-HSA-9682385 |
0 |
Pexidartinib |
25151352 |
pubchem |
| Drug resistance of FLT3 mutants |
R-HSA-9702506 |
0 |
Pexidartinib |
25151352 |
pubchem |
| pexidartinib-resistant FLT3 mutants |
R-HSA-9702605 |
0 |
Pexidartinib |
25151352 |
pubchem |
| Vitamin B12 metabolism |
R-HSA-6806664 |
0 |
cob(I)alamin |
69310 |
pubchem |
| phosphatidylcholine biosynthesis |
R-HSA-111883 |
0 |
Cytidine diphosphate choline |
72187 |
pubchem |
| MTHFR deficiency |
R-HSA-200663 |
0 |
Cytidine diphosphate choline |
72187 |
pubchem |
| 3q29 copy number variation syndrome |
R-HSA-2206302 |
0 |
Cytidine diphosphate choline |
72187 |
pubchem |
| Translation inhibitors in chronically activated PDGFRA cells |
0 |
0 |
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol |
72276 |
pubchem |
| Vemurafenib Pathway, Pharmacodynamics |
R-ALL-6802253 |
0 |
Vemurafenib |
42611257 |
pubchem |
| Melanoma |
Q9UHD0-PRO_0000015379 |
map05218 |
Vemurafenib |
42611257 |
pubchem |
| Vinorelbine Action Pathway |
R-HSA-9639775 |
0 |
Vinorelbine Ditartarate |
72277 |
pubchem |