| GENE_SYMBOL |
HGNC_ID |
UNIPROT_ID |
DRUG_NAME |
PUBCHEM_CID |
Datasource |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-1-acetylpyrrolidine-2-carbonyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
89702121 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
(3S)-N-[(3,5-difluorophenyl)methyl]-3-hydroxy-1-(1H-indol-5-yl)-2-oxopyrrolidine-3-carboxamide |
89855776 |
DGidb |
| VHL |
HGNC:12687 |
P40337 |
PROTAC RIPK degrader-2 |
91799297 |
ChemBL, TTD |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-1-acetylpiperidine-2-carbonyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
117720179 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
Belzutifan |
117947097 |
DGidb, PharmGKB |
| VHL |
HGNC:12687 |
P40337 |
Zimlovisertib |
118414016 |
Pubchem |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-2-acetamido-2-phenylacetyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
118717523 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-2-[[(2S)-2-acetamidopropanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
118717524 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-2-[[(2S)-2-acetamido-2-phenylacetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
118717557 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
(3S)-2-acetyl-N-[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]-3,4-dihydro-1H-isoquinoline-3-carboxamide |
118717558 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
(2S)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
118886738 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
VH298 |
122199236 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
122201421 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
US10730870, Example 21 |
122529112 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-2-acetamido-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide |
122529139 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
Arv-771 |
126619980 |
ChemBL, DGidb |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide |
126654553 |
ChemBL |
| VHL |
HGNC:12687 |
P40337 |
Adagrasib |
138611145 |
Pubchem |
| VHL |
HGNC:12687 |
P40337 |
DT2216 |
139331475 |
Pubchem |
| VHL |
HGNC:12687 |
P40337 |
(2S,4R)-1-((R)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-3-(methylamino)-1-(4-(4-methylthiazol-5-yl)phenyl)-3-oxopropyl)pyrrolidine-2-carboxamide |
153633178 |
ChemBL |