| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| SELE |
(2S)-2-[[(3R,5R)-1,3,4,5-tetrahydroxycyclohexanecarbonyl]amino]propanoic acid |
NA |
50000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
2-[5-[2-[[2-[3-(2,3,4-Trihydroxyphenyl)phenyl]acetyl]amino]phenyl]thiophen-2-yl]acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
(2S,4S,5R,6R)-5-acetamido-2-[(2R,3S,4S,5R,6R)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(1R,2R)-2-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxycyclohexyl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid |
NA |
600000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
sialyl Lewis(x) |
NA |
1000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
3-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid |
NA |
2500000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(2S,4S,5R,6R)-5-acetamido-2-((2S,3R,4S,5S,6R)-2-((2R,3S,4R,5R)-5-acetamido-1,2-dihydroxy-6-oxo-4-((2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)hexan-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid |
NA |
300000 |
NA |
NA |
NA |
NA |
BindingDB |
| SELE |
(S)-2-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid |
NA |
11000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
3-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid |
NA |
5000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(S)-2-(2,2-difluoro-2-((2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid |
NA |
3000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
3-(2,2-difluoro-2-((2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid |
NA |
5000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(S)-2-(2,2-difluoro-2-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid |
NA |
15000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
beta-Mannosylglutamate |
NA |
6000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
sodium;(2S)-2-[2-(aminomethyl)-3,5-dihydroxy-6-[2-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxycyclohexyl]oxyoxan-4-yl]oxy-3-phenylpropanoate |
NA |
10000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
Sialyl Lewis X Antigen |
NA |
NA|300000|500000|600000|700000|1090000|3000000|3300000|5000000 |
1000000|NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(2S,4R,5R,6R)-5-acetamido-2-[(2R,3S,4S,5R,6R)-2-[(1R,2R,3R,4R,6S)-3-acetamido-6-(hydroxymethyl)-4-(9-methoxy-9-oxononoxy)-2-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxycyclohexyl]oxy-3,5,6-trihydroxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid |
NA |
889000|1125000|1170000|1179000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
(2R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R)-1,4-dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid |
NA |
5460000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
1-[4-methoxy-3-[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]phenyl]cyclohexane-1-carboxylic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
1-[4-methoxy-3-[(2R,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]phenyl]cyclohexane-1-carboxylic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| SELE |
2-[(2S,3S,4S,5S,6R)-3,5-dihydroxy-2-(hydroxymethyl)-6-[3-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yloxy]oxan-4-yl]oxyacetic acid |
NA |
2100000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| SELE |
2-[3-[5-[6-[3-[2-(carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-6-oxohexanoyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid |
NA |
1000000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |