| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| USP2 |
4-(1,2,3-Thiadiazol-4-Yl)Benzylamine Hydrochloride |
NA |
5000000 |
NA |
NA |
NA |
NA |
TTD |
| USP2 |
[5-(Thiophen-2-yl)-1,2-oxazol-3-yl]methanol |
NA |
NA|1300000 |
900000|NA |
NA |
NA |
NA |
BindingDB|TTD |
| USP5 |
[4-[4-[1-[[2,4-Dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-4-oxobutyl]-trimethylazanium |
NA |
NA |
170000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
2-[6-[4-[1-[[2,4-Dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]cyclopentanecarbonyl]piperazin-1-yl]-6-oxohexyl]guanidine |
NA |
NA |
130000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
2-(6-Bromo-4-oxo-3,4-dihydroquinazolin-3-yl)acetic acid |
NA |
NA |
250000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
2-(2H-indazol-2-yl)acetic acid |
NA |
NA |
930000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
4-Oxo-4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)butanoic acid |
NA |
NA |
190000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
4-(2,3-dihydro-1H-inden-5-yl)-4-oxobutanoic acid |
NA |
NA |
540000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
4-(4-Isobutylphenyl)-4-oxobutanoic acid |
NA |
NA |
390000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
[(4S)-4-amino-5-[4-[4-[[2,4-dichloro-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]phenyl]sulfonylamino]-1-methylpiperidine-4-carbonyl]piperazin-1-yl]-5-oxopentyl]-trimethylazanium |
NA |
NA |
110000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
2,4-dichloro-N-[1-[4-[(2S)-2,6-diaminohexanoyl]piperazine-1-carbonyl]cyclopentyl]-3-[(2,4-dimethylquinolin-8-yl)oxymethyl]benzenesulfonamide |
NA |
NA |
270000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
3-{5-[3-(Trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-yl}propanoic acid |
NA |
NA |
920000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
4-(4-Tert-butylphenyl)-4-oxobutanoic acid |
NA |
NA |
170000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
4-(Naphthalen-2-yl)-4-oxobutanoic acid |
NA |
NA |
490000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
3-(7-methoxy-4-methyl-2-oxo-2H-chromen-6-yl)propanoic acid |
NA |
NA |
250000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
3-[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]propanoic acid |
NA |
NA |
450000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
3-(5-Phenyl-1,3-oxazol-2-yl)propanoic acid |
NA |
NA |
910000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
H-Asp-D-Pen(1)-Phe-Trp-Orn-Tyr-Cys(1)-Val-OH |
NA |
NA |
150000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(5-methoxyfuran-2-yl)methanone |
NA |
NA |
220000 |
NA |
NA |
NA |
BindingDB |
| USP5 |
[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-phenylmethanone |
NA |
NA |
130000 |
NA |
NA |
NA |
BindingDB |