| GENE_SYMBOL |
DRUG_NAME |
Ki (nM) |
IC50 (nM) |
Kd (nM) |
EC50 (nM) |
Potency (nM) |
AC50 (nM) |
Datasource |
| XPNPEP1 |
(S)-1-[(S)-1-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyryl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carboxylic acid amide |
NA |
250000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
Methyl ((2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl)-L-prolinate |
NA |
122000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (2S)-1-[(2S,3R)-3-amino-2-hydroxy-4-methylpentanoyl]pyrrolidine-2-carboxylate |
NA |
190000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
(2S)-1-[(2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl]-N-methoxypyrrolidine-2-carboxamide |
NA |
303000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (2S)-1-[(2S,3R)-3-amino-6,6,6-trifluoro-2-hydroxyhexanoyl]pyrrolidine-2-carboxylate |
NA |
115000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (2S)-1-[(2S,3R)-3-amino-2-hydroxy-3-phenylpropanoyl]pyrrolidine-2-carboxylate |
NA |
203000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (2S,4S)-1-[(2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl]-4-hydroxypyrrolidine-2-carboxylate |
NA |
190000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (2S)-1-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]pyrrolidine-2-carboxylate |
NA |
241000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (6S)-5-[(2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl]-5-azaspiro[2.4]heptane-6-carboxylate |
NA |
324000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (2S,4S)-1-[(2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl]-4-methylpyrrolidine-2-carboxylate |
NA |
154000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
(2S)-1-[(2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl]-N-(3-methylbutyl)pyrrolidine-2-carboxamide |
NA |
140000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
methyl (2S)-1-[(2S,3R)-3-amino-2,7-dihydroxyheptanoyl]pyrrolidine-2-carboxylate |
NA |
115000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP1 |
Bestatin Methyl Ester |
NA |
298000 |
NA |
NA |
NA |
NA |
BindingDB |
| XPNPEP2 |
H-Sta(3R,4S)-Pro-Ala-NH2 |
NA |
1000000 |
NA |
NA |
NA |
NA |
TTD |
| XPNPEP2 |
H-bAla(2S-OH,3R-Bn)-Hyp-Pro-Ala-NH2 |
NA |
470000 |
NA |
NA |
NA |
NA |
TTD |
| YEATS4 |
[5-(Tert-butyl)-2-thienyl](1-pyrrolidinyl)methanone |
NA |
210000 |
NA |
NA |
NA |
NA |
BindingDB |
| YES1 |
[4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-(ethoxy-hydroxy-phosphoryl)-phenoxy]-acetic acid |
NA |
156000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| YES1 |
(4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid |
NA |
110000 |
NA |
NA |
NA |
NA |
BindingDB|TTD |
| YES1 |
Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenyl ester |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |
| YES1 |
{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-benzylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid |
NA |
500000 |
NA |
NA |
NA |
NA |
TTD |