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drugs and pathways
negative DTIs
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Drug-Pathway
DRUGs and PATHWAYs
Pathway
Drug
PATHWAY_NAME
REACTOME_ID
KEGG_ID
DRUG_NAME
PUBCHEM_CID
Datasource
Postsynaptic nicotinic acetylcholine receptors
R-HSA-622327
0
Sodium ion
135403647
pubchem
Glutamate binding, activation of AMPA receptors and synaptic plasticity
0
0
Sodium ion
135403647
pubchem
Activation of AMPA receptors
R-HSA-399710
0
Sodium ion
135403647
pubchem
Activation of NMDA receptors and postsynaptic events
0
0
Sodium ion
135403647
pubchem
Unblocking of NMDA receptors, glutamate binding and activation
0
0
Sodium ion
135403647
pubchem
Activation of kainate receptors upon glutamate binding
0
0
Sodium ion
135403647
pubchem
Ionotropic activity of kainate receptors
R-HSA-451306
0
Sodium ion
135403647
pubchem
Activation of Na-permeable kainate receptors
R-HSA-451307
0
Sodium ion
135403647
pubchem
Metabolism of proteins
R-HSA-392499
0
Sodium ion
135403647
pubchem
Surfactant metabolism
R-HSA-5683826
0
Sodium ion
135403647
pubchem
Disease
R-HSA-1643685
0
Sodium ion
135403647
pubchem
Disorders of transmembrane transporters
R-HSA-5619115
0
Sodium ion
135403647
pubchem
SLC transporter disorders
R-HSA-5619102
0
Sodium ion
135403647
pubchem
Defective SLC12A1 causes Bartter syndrome 1
#N/A
#N/A
Sodium ion
135403647
pubchem
Defective SLC12A3 causes Gitelman syndrome
#N/A
#N/A
Sodium ion
135403647
pubchem
Defective SLC1A1 is implicated in schizophrenia 18 and dicarboxylic aminoaciduria
#N/A
#N/A
Sodium ion
135403647
pubchem
Defective SLC1A3 causes episodic ataxia 6
#N/A
#N/A
Sodium ion
135403647
pubchem
Defective SLC20A2 causes idiopathic basal ganglia calcification 1
#N/A
#N/A
Sodium ion
135403647
pubchem
Defective SLC22A5 causes systemic primary carnitine deficiency
#N/A
#N/A
Sodium ion
135403647
pubchem
Defective SLC24A1 causes congenital stationary night blindness 1D
#N/A
#N/A
Sodium ion
135403647
pubchem
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