LncRNA:ENSG00000231607

Official Symbol

DLEU2  provided by HGNC

Official Full Name

deleted in lymphocytic leukemia 2 

Gene ID

8847 

Chromosome

chr13

Start Site

49956670

End Site

50125720

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

ALT1|BCMSUN|DLB2|LEU2|LINC00022|MIR15AHG|NCRNA00022|RFP2|RFP2OS|TRIM13OS 

Summary

This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000165819

Official Symbol

METTL3  provided by HGNC

Official Full Name

"methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit" 

m6A Category

writers 

Gene ID

56339 

Chromosome

chr14 

Start Site

21498133 

End Site

21511342 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IME4|M6A|MT-A70|Spo8|hMETTL3 

Summary

"This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol DLEU2  METTL3 
Pvalue 5.1e-05  5.8e-04 
Log2FC 2.5e+00  9.6e-01 
Significant UP REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.36 
Correlation FDR 1.5e-05