1. Overview of Lnc2m6A

N6-methyladenosine (m6A) palys essential roles in tumorigenesis and cancer progression. Long noncoding RNAs (lncRNAs) are emerging as important targets of m6A modification and they play fundamental roles in diverse biological processes. However, our knowledge regarding the association between m6A and lncRNAs in human tumors is still lacking. Here, we comprehensively explored the relationship between lncRNAs and 21 m6A regulators through integrating multi-omics data. In this resource, the users can query t he m6A-related lncRNAs with ceRNA networks, drug sensitivity and clinical survival across 33 cancer types. The Lnc2m6A will provide a valuable resource that guide both mechanistic and therapeutic roles of m6A-related lncRNAs in human tumors

2. Search

Users can select a cancer type, enter the category of lncRNAs and m6A regulators to scan their relationships in detail.

3. Result

You can get the result through the way described above. In this page, we provide id, symbol, correlation coefficients, p-value, FDR and tumor type of interested lncRNAs and m6A regulators. Users also can see the details of the relationship between lncRNAs and m6A regulators by clicking details.

4. Tools

4.1 ceRNA networks

Users can select a cancer type, lncRNA ID or lncRNA symbol to scan the information of m6A-related lncRNAs involved ceRNA network in specific cancer type.

In this page, we provide id, symbol for lncRNA, mRNA and miRNA in the ceRNA network. Users also can see the details of the ceRNA network by clicking details. The ceRNA network can be shown by clicking ‘Show the data as network’ button. The relationship between lncRNAs and m6A regulators can be shown by clicking ‘Show the related m6A regulator’ button.

4.2 drug sensitivity

Users can select a cancer type, lncRNA ID or drug symbol to estimate the relationship between m6A-related lncRNAs and drug sensitivity in specific cancer type.

In this page, we provide id, symbol, drug name, ES score, p-value, FDR and tumor type of interested lncRNAs and drugs. The relationship between lncRNAs and m6A regulators can be shown by clicking ‘To m6A regulator’ button.

4.3 clinical survival

Users can select a cancer type, lncRNA ID or lncRNA symbol to estimate the clinical association of m6A-related lncRNAs in specific cancer type.

In this page, we provide id, symbol, HR, Log-rank p value and tumor type of interested lncRNAs. The relationship between lncRNAs and m6A regulators can be shown by clicking ‘Link to related m6A regulator’.

5. Download

In addition, download links are provided, which allow the user to batch download information they interested in