Official Symbol

ZEB1-AS1  provided by HGNC

Official Full Name

ZEB1 antisense RNA 1 

Gene ID

220930 

Chromosome

chr10

Start Site

31206278

End Site

31320447

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

- 

Summary

This locus produces long non-coding RNA that is transcribed from a shared bi-directional promoter with zinc finger E-box binding homeobox 1 (ZEB1). This transcript binds lysine methyltransferase 2A and promotes histone modifications that are thought to promote expression of ZEB1. Expression of this gene is correlated with tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017] 

Official Symbol

YTHDF2  provided by HGNC

Official Full Name

YTH N6-methyladenosine RNA binding protein 2 

m6A Category

readers 

Gene ID

51441 

Chromosome

chr1 

Start Site

28736621 

End Site

28769775 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

CAHL|DF2|HGRG8|NY-REN-2 

Summary

"This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]"