Official Symbol

PCBP1-AS1  provided by HGNC

Official Full Name

aspartic peptidase retroviral like 1 

Gene ID

151516 

Chromosome

chr2

Start Site

69962263

End Site

70103220

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

ADLI|MUNO|SASP|SASPase|Taps 

Summary

Filaggrin is a structural protein that is crucial for in the development and maintenance of the skin barrier. This gene encodes a retroviral-like protease involved in profilaggrin-to-filaggrin processing. Expression is found primarily in the epidermis and inner root sheath of hair follicles. [provided by RefSeq, May 2017] 

Official Symbol

FTO  provided by HGNC

Official Full Name

FTO alpha-ketoglutarate dependent dioxygenase 

m6A Category

erasers 

Gene ID

79068 

Chromosome

chr16 

Start Site

53701692 

End Site

54158512 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

ALKBH9|BMIQ14|GDFD 

Summary

"This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]"