Official Symbol

ZEB1-AS1  provided by HGNC

Official Full Name

ZEB1 antisense RNA 1 

Gene ID

220930 

Chromosome

chr10

Start Site

31206278

End Site

31320447

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

- 

Summary

This locus produces long non-coding RNA that is transcribed from a shared bi-directional promoter with zinc finger E-box binding homeobox 1 (ZEB1). This transcript binds lysine methyltransferase 2A and promotes histone modifications that are thought to promote expression of ZEB1. Expression of this gene is correlated with tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017] 

Official Symbol

FTO  provided by HGNC

Official Full Name

FTO alpha-ketoglutarate dependent dioxygenase 

m6A Category

erasers 

Gene ID

79068 

Chromosome

chr16 

Start Site

53701692 

End Site

54158512 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

ALKBH9|BMIQ14|GDFD 

Summary

"This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]"