LncRNA:ENSG00000225783

Official Symbol

MIAT  provided by HGNC

Official Full Name

myocardial infarction associated transcript 

Gene ID

440823 

Chromosome

chr22

Start Site

26646411

End Site

26676475

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

C22orf35|GOMAFU|LINC00066|NCRNA00066|RNCR2|lncRNA-MIAT 

Summary

This gene encodes a spliced long non-coding RNA that may constitute a component of the nuclear matrix. Altered expression of this locus has been reported to be associated with a susceptibility to myocardial infarction. It has also been proposed that pathways involving this transcript may contribute to the pathophysiology of schizophrenia. A similar gene in mouse has been associated with retinal cell fate determination. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2014] 

M6ARegulator:ENSG00000092199

Official Symbol

HNRNPC  provided by HGNC

Official Full Name

heterogeneous nuclear ribonucleoprotein C 

m6A Category

readers 

Gene ID

3183 

Chromosome

chr14 

Start Site

21209136 

End Site

21269494 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

C1|C2|HNRNP|HNRPC|SNRPC 

Summary

"This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol MIAT  HNRNPC 
Pvalue 9.2e-01  1.7e-25 
Log2FC 3.1e-02  -1.5e+00 
Significant NOT SIGNIFICANT  DOWN REGULATED 
Correlation coefficient 0.4 
Correlation FDR 6.5e-03