LncRNA:ENSG00000177410

Official Symbol

ZFAS1  provided by HGNC

Official Full Name

ZNFX1 antisense RNA 1 

Gene ID

441951 

Chromosome

chr20

Start Site

49278178

End Site

49299600

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

C20orf199|HSUP1|HSUP2|NCRNA00275|ZNFX1-AS1 

Summary

This gene represents a snoRNA host gene that produces a non-coding RNA. Increased expression or amplification of this locus is associated with cancer progression and metastasis. This transcript regulates expression of genes involved in differentiation. It may act a molecular sponge for microRNAs. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000047188

Official Symbol

YTHDC2  provided by HGNC

Official Full Name

YTH domain containing 2 

m6A Category

readers 

Gene ID

64848 

Chromosome

chr5 

Start Site

113513694 

End Site

113595285 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CAHL|hYTHDC2 

Summary

"This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]" 

Differentially expressed Detail
Symbol ZFAS1  YTHDC2 
Pvalue 2.6e-02  4.3e-06 
Log2FC -3.2e-01  -5.8e-01 
Significant NOT SIGNIFICANT  NOT SIGNIFICANT 
Correlation coefficient 0.33 
Correlation FDR 3.1e-02