LncRNA:ENSG00000240990

Official Symbol

HOXA11-AS  provided by HGNC

Official Full Name

HOXA11 antisense RNA 

Gene ID

221883 

Chromosome

chr7

Start Site

27184507

End Site

27189298

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

HOXA-AS5|HOXA11-AS1|HOXA11AS|HOXA11S|NCRNA00076 

Summary

This gene produces a long non-coding RNA in antisense to transcription of the homeobox A11 gene. This transcript may associate with chromatin factors such as Polycomb repressive complex and act as a sponge for microRNAs, thereby participating in the regulation of expression of target genes. High levels of this transcript may be associated with tumor progression. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000165819

Official Symbol

METTL3  provided by HGNC

Official Full Name

"methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit" 

m6A Category

writers 

Gene ID

56339 

Chromosome

chr14 

Start Site

21498133 

End Site

21511342 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IME4|M6A|MT-A70|Spo8|hMETTL3 

Summary

"This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol HOXA11-AS  METTL3 
Pvalue 2.5e-04  8.9e-06 
Log2FC -1.4e+00  -4.6e-01 
Significant DOWN REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.3 
Correlation FDR 4.9e-02