LncRNA:ENSG00000231607

Official Symbol

DLEU2  provided by HGNC

Official Full Name

deleted in lymphocytic leukemia 2 

Gene ID

8847 

Chromosome

chr13

Start Site

49956670

End Site

50125720

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

ALT1|BCMSUN|DLB2|LEU2|LINC00022|MIR15AHG|NCRNA00022|RFP2|RFP2OS|TRIM13OS 

Summary

This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000162775

Official Symbol

RBM15  provided by HGNC

Official Full Name

RNA binding motif protein 15 

m6A Category

writers 

Gene ID

64783 

Chromosome

chr1 

Start Site

110338506 

End Site

110346681 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

OTT|OTT1|SPEN 

Summary

"Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]" 

Differentially expressed Detail
Symbol DLEU2  RBM15 
Pvalue 2.3e-07  1.4e-07 
Log2FC -1.2e+00  -8.0e-01 
Significant DOWN REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.65 
Correlation FDR 2.8e-07