Official Symbol

HOTAIR  provided by HGNC

Official Full Name

HOX transcript antisense RNA 

Gene ID

100124700 

Chromosome

chr12

Start Site

53962308

End Site

53974956

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

HOXAS|HOXC-AS4|HOXC11-AS1|NCRNA00072 

Summary

This gene is located within the Homeobox C (HOXC) gene cluster on chromosome 12 and is co-expressed with the HOXC genes. It functions through an RNA product, which binds lysine specific demethylase 1 (LSD1) and Polycomb repressive complex 2 (PRC2), and serves as a scaffold to assemble these regulators at the HOXD gene cluster, thereby promoting epigenetic repression of HOXD. This gene is highly expressed in multiple tumors. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Feb 2019] 

Official Symbol

IGF2BP1  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 1 

m6A Category

readers 

Gene ID

10642 

Chromosome

chr17 

Start Site

48997385 

End Site

49056145 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

CRD-BP|CRDBP|IMP-1|IMP1|VICKZ1|ZBP1 

Summary

"This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]"