LncRNA:ENSG00000253438

Official Symbol

PCAT1  provided by HGNC

Official Full Name

prostate cancer associated transcript 1 

Gene ID

100750225 

Chromosome

chr8

Start Site

126556323

End Site

127419050

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

PCA1|PCAT-1|PiHL 

Summary

This gene produces a long non-coding RNA that promotes cell proliferation and is upregulated in prostate, colorectal, and other cancers. This RNA negatively regulates the BRCA2 tumor suppressor protein and positively regulates Myc oncoprotein. It contains binding sites for microRNAs, and may act as a sponge for microRNAs that regulate cell growth pathways. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000165819

Official Symbol

METTL3  provided by HGNC

Official Full Name

"methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit" 

m6A Category

writers 

Gene ID

56339 

Chromosome

chr14 

Start Site

21498133 

End Site

21511342 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IME4|M6A|MT-A70|Spo8|hMETTL3 

Summary

"This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol PCAT1  METTL3 
Pvalue 1.9e-01  3.0e-01 
Log2FC 2.9e-01  9.0e-02 
Significant NOT SIGNIFICANT  NOT SIGNIFICANT 
Correlation coefficient 0.34 
Correlation FDR 1.6e-08