LncRNA:ENSG00000245526

Official Symbol

LINC00461  provided by HGNC

Official Full Name

long intergenic non-protein coding RNA 461 

Gene ID

645323 

Chromosome

chr5

Start Site

88507546

End Site

88691057

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

ECONEXIN|EyeLinc1|NDIME|VISC 

Summary

This is an evolutionarily conserved gene that produces alternatively spliced long non-coding RNAs that may be expressed predominantly in the brain and visual cortex. These transcripts may be involved in tumorigenesis, as depletion by siRNA suppressed glioma cell division. Transcripts may also bind to and regulate the activity of miR-411-5p and argonaut 2, thereby altering the expression of genes involved in tumor growth. [provided by RefSeq, Nov 2017] 

M6ARegulator:ENSG00000165819

Official Symbol

METTL3  provided by HGNC

Official Full Name

"methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit" 

m6A Category

writers 

Gene ID

56339 

Chromosome

chr14 

Start Site

21498133 

End Site

21511342 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IME4|M6A|MT-A70|Spo8|hMETTL3 

Summary

"This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol LINC00461  METTL3 
Pvalue Not Available  Not Available 
Log2FC Not Available  Not Available 
Significant Not Available  Not Available 
Correlation coefficient 0.35 
Correlation FDR 1.9e-15