LncRNA:ENSG00000255717

Official Symbol

SNHG1  provided by HGNC

Official Full Name

small nucleolar RNA host gene 1 

Gene ID

23642 

Chromosome

chr11

Start Site

62851984

End Site

62855953

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

LINC00057|NCRNA00057|U22HG|UHG|lncRNA16 

Summary

This locus represents a small nucleolar RNA host gene that produces multiple alternatively spliced long non-coding RNAs. This gene is upregulated in cancers and is thought to act as promoter of cell proliferation. This transcript negatively regulates tumor suppressor genes such as tumor protein p53. Expression of this locus may be a marker of tumor progression. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000165819

Official Symbol

METTL3  provided by HGNC

Official Full Name

"methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit" 

m6A Category

writers 

Gene ID

56339 

Chromosome

chr14 

Start Site

21498133 

End Site

21511342 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IME4|M6A|MT-A70|Spo8|hMETTL3 

Summary

"This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol SNHG1  METTL3 
Pvalue 3.4e-26  9.8e-29 
Log2FC 2.2e+00  1.3e+00 
Significant UP REGULATED  UP REGULATED 
Correlation coefficient 0.59 
Correlation FDR 1.1e-34