Official Symbol

MIR17HG  provided by HGNC

Official Full Name

miR-17-92a-1 cluster host gene 

Gene ID

407975 

Chromosome

chr13

Start Site

91347820

End Site

91354579

Strand

+ 

Assembly

GRCh38

Biotype

lncRNA

Also known as

C13orf25|FGLDS2|LINC00048|MIHG1|MIRH1|MIRHG1|NCRNA00048|miR-17-92 

Summary

This gene is the host gene for the MIR17-92 cluster, a group of at least six microRNAs (miRNAs) that may be involved in cell survival, proliferation, differentiation, and angiogenesis. Amplification of this gene has been found in several lymphomas and solid tumors. Two non-protein coding transcript variants have been found for this host gene, but only the longest is a polycistronic transcript containing the MIR17-92 cluster. [provided by RefSeq, May 2012] 

Official Symbol

YTHDC2  provided by HGNC

Official Full Name

YTH domain containing 2 

m6A Category

readers 

Gene ID

64848 

Chromosome

chr5 

Start Site

113513694 

End Site

113595285 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

CAHL|hYTHDC2 

Summary

"This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]"