LncRNA:ENSG00000231607

Official Symbol

DLEU2  provided by HGNC

Official Full Name

deleted in lymphocytic leukemia 2 

Gene ID

8847 

Chromosome

chr13

Start Site

49956670

End Site

50125720

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

ALT1|BCMSUN|DLB2|LEU2|LINC00022|MIR15AHG|NCRNA00022|RFP2|RFP2OS|TRIM13OS 

Summary

This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000136231

Official Symbol

IGF2BP3  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 3 

m6A Category

readers 

Gene ID

10643 

Chromosome

chr7 

Start Site

23310209 

End Site

23470491 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CT98|IMP-3|IMP3|KOC|KOC1|VICKZ3 

Summary

"The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol DLEU2  IGF2BP3 
Pvalue Not Available  Not Available 
Log2FC Not Available  Not Available 
Significant Not Available  Not Available 
Correlation coefficient 0.4 
Correlation FDR 1.9e-03