LncRNA:ENSG00000231607

Official Symbol

DLEU2  provided by HGNC

Official Full Name

deleted in lymphocytic leukemia 2 

Gene ID

8847 

Chromosome

chr13

Start Site

49956670

End Site

50125720

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

ALT1|BCMSUN|DLB2|LEU2|LINC00022|MIR15AHG|NCRNA00022|RFP2|RFP2OS|TRIM13OS 

Summary

This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000073792

Official Symbol

IGF2BP2  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 2 

m6A Category

readers 

Gene ID

10644 

Chromosome

chr3 

Start Site

185643130 

End Site

185825042 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IMP-2|IMP2|VICKZ2 

Summary

"This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]" 

Differentially expressed Detail
Symbol DLEU2  IGF2BP2 
Pvalue Not Available  Not Available 
Log2FC Not Available  Not Available 
Significant Not Available  Not Available 
Correlation coefficient 0.36 
Correlation FDR 6.9e-14