Official Symbol

WT1-AS  provided by HGNC

Official Full Name

WT1 antisense RNA 

Gene ID

51352 

Chromosome

chr11

Start Site

32435518

End Site

32458769

Strand

+ 

Assembly

GRCh38

Biotype

lncRNA

Also known as

WIT-1|WIT1|WT1-AS1|WT1AS 

Summary

This gene is located upstream of the Wilms tumor 1 (WT1) gene; these two genes are bi-directionally transcribed from the same promoter region. This gene is imprinted in kidney, with preferential expression from the paternal allele. Imprinting defects at chromosome 11p13 may contribute to tumorigenesis. [provided by RefSeq, May 2014] 

Official Symbol

YTHDF2  provided by HGNC

Official Full Name

YTH N6-methyladenosine RNA binding protein 2 

m6A Category

readers 

Gene ID

51441 

Chromosome

chr1 

Start Site

28736621 

End Site

28769775 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

CAHL|DF2|HGRG8|NY-REN-2 

Summary

"This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]"