Official Symbol

MEG3  provided by HGNC

Official Full Name

maternally expressed 3 

Gene ID

55384 

Chromosome

chr14

Start Site

100779410

End Site

100861031

Strand

+ 

Assembly

GRCh38

Biotype

lncRNA

Also known as

FP504|GTL2|LINC00023|NCRNA00023|PRO0518|PRO2160|onco-lncRNA-83|prebp1 

Summary

This gene is a maternally expressed imprinted gene. Multiple alternatively spliced transcript variants have been transcribed from this gene and all of them are long non-coding RNAs (lncRNAs). This gene is expressed in many normal tissues, but its expression is lost in multiple cancer cell lines of various tissue origins. It inhibits tumor cell proliferation in vitro. It also interacts with the tumor suppressor p53, and regulates p53 target gene expression. Its deletion enhances angiogenesis in vivo. Many experimental evidences demonstrate that this gene is a lncRNA tumor suppressor. [provided by RefSeq, Mar 2012] 

Official Symbol

YTHDF3  provided by HGNC

Official Full Name

YTH N6-methyladenosine RNA binding protein 3 

m6A Category

readers 

Gene ID

253943 

Chromosome

chr8 

Start Site

63168553 

End Site

63212786 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

DF3 

Summary

"This gene encodes a member of the YTH (YT521-B homology) domain protein family. The YTH domain is common in eukaryotes, is often found in the middle of the protein sequence, and may function in binding to RNA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]"