Official Symbol

MEG3  provided by HGNC

Official Full Name

maternally expressed 3 

Gene ID

55384 

Chromosome

chr14

Start Site

100779410

End Site

100861031

Strand

+ 

Assembly

GRCh38

Biotype

lncRNA

Also known as

FP504|GTL2|LINC00023|NCRNA00023|PRO0518|PRO2160|onco-lncRNA-83|prebp1 

Summary

This gene is a maternally expressed imprinted gene. Multiple alternatively spliced transcript variants have been transcribed from this gene and all of them are long non-coding RNAs (lncRNAs). This gene is expressed in many normal tissues, but its expression is lost in multiple cancer cell lines of various tissue origins. It inhibits tumor cell proliferation in vitro. It also interacts with the tumor suppressor p53, and regulates p53 target gene expression. Its deletion enhances angiogenesis in vivo. Many experimental evidences demonstrate that this gene is a lncRNA tumor suppressor. [provided by RefSeq, Mar 2012] 

Official Symbol

RBM15B  provided by HGNC

Official Full Name

RNA binding motif protein 15B 

m6A Category

writers 

Gene ID

29890 

Chromosome

chr3 

Start Site

51391285 

End Site

51397908 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

HUMAGCGB|HsOTT3|OTT3 

Summary

"Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]"