LncRNA:ENSG00000099869

Official Symbol

IGF2-AS  provided by HGNC

Official Full Name

IGF2 antisense RNA 

Gene ID

51214 

Chromosome

chr11

Start Site

2140501

End Site

2148666

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

IGF2-AS1|IGF2AS|PEG8 

Summary

This gene is expressed in antisense to the insulin-like growth factor 2 (IGF2) gene and is imprinted and paternally expressed. It is thought to be non-coding because the putative protein is not conserved and translation is predicted to trigger nonsense mediated decay (NMD). Transcripts from this gene are produced in tumors and may function to suppress cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015] 

M6ARegulator:ENSG00000136231

Official Symbol

IGF2BP3  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 3 

m6A Category

readers 

Gene ID

10643 

Chromosome

chr7 

Start Site

23310209 

End Site

23470491 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CT98|IMP-3|IMP3|KOC|KOC1|VICKZ3 

Summary

"The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol IGF2-AS  IGF2BP3 
Pvalue Not Available  Not Available 
Log2FC Not Available  Not Available 
Significant Not Available  Not Available 
Correlation coefficient 0.31 
Correlation FDR 1.2e-04