LncRNA:ENSG00000215417

Official Symbol

MIR17HG  provided by HGNC

Official Full Name

miR-17-92a-1 cluster host gene 

Gene ID

407975 

Chromosome

chr13

Start Site

91347820

End Site

91354579

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

C13orf25|FGLDS2|LINC00048|MIHG1|MIRH1|MIRHG1|NCRNA00048|miR-17-92 

Summary

This gene is the host gene for the MIR17-92 cluster, a group of at least six microRNAs (miRNAs) that may be involved in cell survival, proliferation, differentiation, and angiogenesis. Amplification of this gene has been found in several lymphomas and solid tumors. Two non-protein coding transcript variants have been found for this host gene, but only the longest is a polycistronic transcript containing the MIR17-92 cluster. [provided by RefSeq, May 2012] 

M6ARegulator:ENSG00000073792

Official Symbol

IGF2BP2  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 2 

m6A Category

readers 

Gene ID

10644 

Chromosome

chr3 

Start Site

185643130 

End Site

185825042 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IMP-2|IMP2|VICKZ2 

Summary

"This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]" 

Differentially expressed Detail
Symbol MIR17HG  IGF2BP2 
Pvalue 5.2e-07  1.2e-02 
Log2FC 3.0e+00  6.2e-01 
Significant UP REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.3 
Correlation FDR 2.0e-02