LncRNA:ENSG00000213468

Official Symbol

FIRRE  provided by HGNC

Official Full Name

firre intergenic repeating RNA element 

Gene ID

286467 

Chromosome

chrX

Start Site

131688779

End Site

131830862

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

LINC01200 

Summary

This gene produces a long RNA containing a repeating sequence. This RNA interacts with heterogeneous nuclear ribonucleoprotein U and coats chromosomes, where it plays an important role in the maintenance of repressive chromatin. This transcript can also act post-transcriptionally to regulate the stability of mRNAs during the innate immune response. [provided by RefSeq, Dec 2017] 

M6ARegulator:ENSG00000047188

Official Symbol

YTHDC2  provided by HGNC

Official Full Name

YTH domain containing 2 

m6A Category

readers 

Gene ID

64848 

Chromosome

chr5 

Start Site

113513694 

End Site

113595285 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CAHL|hYTHDC2 

Summary

"This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]" 

Differentially expressed Detail
Symbol FIRRE  YTHDC2 
Pvalue 3.2e-07  6.1e-01 
Log2FC 5.7e+00  -8.6e-02 
Significant UP REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.33 
Correlation FDR 8.9e-03