LncRNA:ENSG00000260280

Official Symbol

SLX1B-SULT1A4  provided by HGNC

Official Full Name

SLX1B-SULT1A4 readthrough (NMD candidate) 

Gene ID

100526831 

Chromosome

chr16

Start Site

29455105

End Site

29464963

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

Summary

This locus represents naturally occurring read-through transcription between the neighboring SLX1B (SLX1 structure-specific endonuclease subunit homolog B) and SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) genes on the short arm of chromosome 16. A duplicate read-through locus also exists between the SLX1A and SULT1A3 genes located approximately 730 kb downstream on the same chromosome. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2017] 

M6ARegulator:ENSG00000122566

Official Symbol

HNRNPA2B1  provided by HGNC

Official Full Name

heterogeneous nuclear ribonucleoprotein A2/B1 

m6A Category

readers 

Gene ID

3181 

Chromosome

chr7 

Start Site

26173057 

End Site

26201529 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

HNRNPA2|HNRNPB1|HNRPA2|HNRPA2B1|HNRPB1|IBMPFD2|RNPA2|SNRPB1 

Summary

"This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol SLX1B-SULT1A4  HNRNPA2B1 
Pvalue 1.2e-11  1.8e-15 
Log2FC 1.5e+00  1.2e+00 
Significant UP REGULATED  UP REGULATED 
Correlation coefficient 0.51 
Correlation FDR 1.2e-26