LncRNA:ENSG00000260280

Official Symbol

SLX1B-SULT1A4  provided by HGNC

Official Full Name

SLX1B-SULT1A4 readthrough (NMD candidate) 

Gene ID

100526831 

Chromosome

chr16

Start Site

29455105

End Site

29464963

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

Summary

This locus represents naturally occurring read-through transcription between the neighboring SLX1B (SLX1 structure-specific endonuclease subunit homolog B) and SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) genes on the short arm of chromosome 16. A duplicate read-through locus also exists between the SLX1A and SULT1A3 genes located approximately 730 kb downstream on the same chromosome. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2017] 

M6ARegulator:ENSG00000073792

Official Symbol

IGF2BP2  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 2 

m6A Category

readers 

Gene ID

10644 

Chromosome

chr3 

Start Site

185643130 

End Site

185825042 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

IMP-2|IMP2|VICKZ2 

Summary

"This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]" 

Differentially expressed Detail
Symbol SLX1B-SULT1A4  IGF2BP2 
Pvalue 1.2e-11  1.0e-12 
Log2FC 1.5e+00  2.6e+00 
Significant UP REGULATED  UP REGULATED 
Correlation coefficient 0.32 
Correlation FDR 3.2e-10