Official Symbol
DLEU2 provided by HGNC
Official Full Name
deleted in lymphocytic leukemia 2
Gene ID
8847
Chromosome
chr13
Start Site
49956670
End Site
50125720
Strand
-
Assembly
GRCh38
Biotype
lncRNA
Also known as
ALT1|BCMSUN|DLB2|LEU2|LINC00022|MIR15AHG|NCRNA00022|RFP2|RFP2OS|TRIM13OS
Summary
This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017]