M6ARegulator:ENSG00000140718
Official Symbol
FTO provided by HGNC
Official Full Name
FTO alpha-ketoglutarate dependent dioxygenase
m6A Category
erasers
Gene ID
79068
Chromosome
chr16
Start Site
53701692
End Site
54158512
Strand
+
Assembly
GRCh38
Biotype
protein coding
Also known as
ALKBH9|BMIQ14|GDFD
Summary
"This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]"