Official Symbol

HOTAIR  provided by HGNC

Official Full Name

HOX transcript antisense RNA 

Gene ID

100124700 

Chromosome

chr12

Start Site

53962308

End Site

53974956

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

HOXAS|HOXC-AS4|HOXC11-AS1|NCRNA00072 

Summary

This gene is located within the Homeobox C (HOXC) gene cluster on chromosome 12 and is co-expressed with the HOXC genes. It functions through an RNA product, which binds lysine specific demethylase 1 (LSD1) and Polycomb repressive complex 2 (PRC2), and serves as a scaffold to assemble these regulators at the HOXD gene cluster, thereby promoting epigenetic repression of HOXD. This gene is highly expressed in multiple tumors. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Feb 2019] 

Official Symbol

IGF2BP2  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 2 

m6A Category

readers 

Gene ID

10644 

Chromosome

chr3 

Start Site

185643130 

End Site

185825042 

Strand

- 

Assembly

GRCh38

Biotype

protein coding 

Also known as

IMP-2|IMP2|VICKZ2 

Summary

"This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]"