Official Symbol

XIST  provided by HGNC

Official Full Name

X inactive specific transcript 

Gene ID

7503 

Chromosome

chrX

Start Site

73820649

End Site

73852723

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

DXS1089|DXS399E|LINC00001|NCRNA00001|SXI1|swd66 

Summary

X inactivation is an early developmental process in mammalian females that transcriptionally silences one of the pair of X chromosomes, thus providing dosage equivalence between males and females. The process is regulated by several factors, including a region of chromosome X called the X inactivation center (XIC). The XIC comprises several non-coding and protein-coding genes, and this gene was the first non-coding gene identified within the XIC. This gene is expressed exclusively from the XIC of the inactive X chromosome, and is essential for the initiation and spread of X-inactivation. The transcript is a spliced RNA. Alternatively spliced transcript variants have been identified, but their full length sequences have not been determined. Mutations in the XIST promoter cause familial skewed X inactivation. [provided by RefSeq, Apr 2012] 

Official Symbol

RBMX  provided by HGNC

Official Full Name

RNA binding motif protein X-linked 

m6A Category

readers 

Gene ID

27316 

Chromosome

chrX 

Start Site

136848004 

End Site

136880764 

Strand

- 

Assembly

GRCh38

Biotype

protein coding 

Also known as

HNRNPG|HNRPG|MRXS11|RBMXP1|RBMXRT|RNMX|hnRNP-G 

Summary

"This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns. [provided by RefSeq, Sep 2009]"