Official Symbol

HOTAIR  provided by HGNC

Official Full Name

HOX transcript antisense RNA 

Gene ID

100124700 

Chromosome

chr12

Start Site

53962308

End Site

53974956

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

HOXAS|HOXC-AS4|HOXC11-AS1|NCRNA00072 

Summary

This gene is located within the Homeobox C (HOXC) gene cluster on chromosome 12 and is co-expressed with the HOXC genes. It functions through an RNA product, which binds lysine specific demethylase 1 (LSD1) and Polycomb repressive complex 2 (PRC2), and serves as a scaffold to assemble these regulators at the HOXD gene cluster, thereby promoting epigenetic repression of HOXD. This gene is highly expressed in multiple tumors. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Feb 2019] 

Official Symbol

RBM15B  provided by HGNC

Official Full Name

RNA binding motif protein 15B 

m6A Category

writers 

Gene ID

29890 

Chromosome

chr3 

Start Site

51391285 

End Site

51397908 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

HUMAGCGB|HsOTT3|OTT3 

Summary

"Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]"