Official Symbol

HOTAIR  provided by HGNC

Official Full Name

HOX transcript antisense RNA 

Gene ID

100124700 

Chromosome

chr12

Start Site

53962308

End Site

53974956

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

HOXAS|HOXC-AS4|HOXC11-AS1|NCRNA00072 

Summary

This gene is located within the Homeobox C (HOXC) gene cluster on chromosome 12 and is co-expressed with the HOXC genes. It functions through an RNA product, which binds lysine specific demethylase 1 (LSD1) and Polycomb repressive complex 2 (PRC2), and serves as a scaffold to assemble these regulators at the HOXD gene cluster, thereby promoting epigenetic repression of HOXD. This gene is highly expressed in multiple tumors. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Feb 2019] 

Official Symbol

WTAP  provided by HGNC

Official Full Name

WT1 associated protein 

m6A Category

writers 

Gene ID

9589 

Chromosome

chr6 

Start Site

159725585 

End Site

159756319 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

Mum2 

Summary

"The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012]"