LncRNA:ENSG00000268388

Official Symbol

FENDRR  provided by HGNC

Official Full Name

FOXF1 adjacent non-coding developmental regulatory RNA 

Gene ID

400550 

Chromosome

chr16

Start Site

86474529

End Site

86509099

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

FOXF1-AS1|FOXF1AS1|TCONS_00024240|lincFOXF1|onco-lncRNA-21 

Summary

This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015] 

M6ARegulator:ENSG00000122566

Official Symbol

HNRNPA2B1  provided by HGNC

Official Full Name

heterogeneous nuclear ribonucleoprotein A2/B1 

m6A Category

readers 

Gene ID

3181 

Chromosome

chr7 

Start Site

26173057 

End Site

26201529 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

HNRNPA2|HNRNPB1|HNRPA2|HNRPA2B1|HNRPB1|IBMPFD2|RNPA2|SNRPB1 

Summary

"This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol FENDRR  HNRNPA2B1 
Pvalue 8.1e-24  1.4e-10 
Log2FC -1.8e+00  -3.7e-01 
Significant DOWN REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.39 
Correlation FDR 1.7e-19