Official Symbol

TSIX  provided by HGNC

Official Full Name

TSIX transcript, XIST antisense RNA 

Gene ID

9383 

Chromosome

chrX

Start Site

73792205

End Site

73829231

Strand

+ 

Assembly

GRCh38

Biotype

lncRNA

Also known as

LINC00013|NCRNA00013|XIST-AS|XIST-AS1|XISTAS 

Summary

In mammals, dosage compensation of genes on the X chromosome occurs by X inactivation, which is regulated in cis by the X-inactivation center (XIC) and expression of the XIST non-coding RNA. This gene expresses a non-coding antisense transcript across the 3' end of the XIST locus, and is coexpressed with XIST only from the inactive X chromosome. The mouse ortholog of this locus is required for imprinted X inactivation in extraembryonic tissues and silences Xist through modification of the chromatin structure in the Xist promoter region. In contrast, imprinted X inactivation does not occur in human extraembryonic tissues and transcripts from this locus do not repress XIST expression or affect random X chromosome inactivation in embryonic cells. This transcript is thought to be unspliced and extend over more than 30 kb, but its exact nature has not been determined. [provided by RefSeq, Jul 2008] 

Official Symbol

RBMX  provided by HGNC

Official Full Name

RNA binding motif protein X-linked 

m6A Category

readers 

Gene ID

27316 

Chromosome

chrX 

Start Site

136848004 

End Site

136880764 

Strand

- 

Assembly

GRCh38

Biotype

protein coding 

Also known as

HNRNPG|HNRPG|MRXS11|RBMXP1|RBMXRT|RNMX|hnRNP-G 

Summary

"This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns. [provided by RefSeq, Sep 2009]"