LncRNA:ENSG00000225470

Official Symbol

JPX  provided by HGNC

Official Full Name

JPX transcript, XIST activator 

Gene ID

554203 

Chromosome

chrX

Start Site

73944182

End Site

74070408

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

DCBALD06|ENOX|LINC00183|NCRNA00183 

Summary

JPX is a nonprotein-coding RNA transcribed from a gene within the X-inactivation center (XIC; MIM 314670) that appears to participate in X chromosome inactivation (Tian et al., 2010 [PubMed 21029862]).[supplied by OMIM, Feb 2011] 

M6ARegulator:ENSG00000047188

Official Symbol

YTHDC2  provided by HGNC

Official Full Name

YTH domain containing 2 

m6A Category

readers 

Gene ID

64848 

Chromosome

chr5 

Start Site

113513694 

End Site

113595285 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CAHL|hYTHDC2 

Summary

"This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]" 

Differentially expressed Detail
Symbol JPX  YTHDC2 
Pvalue 7.4e-01  1.8e-05 
Log2FC -1.7e-02  -4.2e-01 
Significant NOT SIGNIFICANT  NOT SIGNIFICANT 
Correlation coefficient 0.3 
Correlation FDR 6.9e-12