LncRNA:ENSG00000261771

Official Symbol

DNAAF4-CCPG1  provided by HGNC

Official Full Name

DNAAF4-CCPG1 readthrough (NMD candidate) 

Gene ID

100533483 

Chromosome

chr15

Start Site

55355248

End Site

55498360

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

DYX1C1-CCPG1 

Summary

This locus represents naturally occurring read-through transcription between the neighboring dyslexia susceptibility 1 candidate 1 (DYX1C1) and cell cycle progression 1 (CCPG1) genes on chromosome 15. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Mar 2011] 

M6ARegulator:ENSG00000198492

Official Symbol

YTHDF2  provided by HGNC

Official Full Name

YTH N6-methyladenosine RNA binding protein 2 

m6A Category

readers 

Gene ID

51441 

Chromosome

chr1 

Start Site

28736621 

End Site

28769775 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CAHL|DF2|HGRG8|NY-REN-2 

Summary

"This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]" 

Differentially expressed Detail
Symbol DNAAF4-CCPG1  YTHDF2 
Pvalue 9.5e-12  4.8e-03 
Log2FC -2.7e+00  -1.4e-01 
Significant DOWN REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.4 
Correlation FDR 1.7e-20