Official Symbol
PWRN1 provided by HGNC
Official Full Name
Prader-Willi region non-protein coding RNA 1
Gene ID
791114
Chromosome
chr15
Start Site
24101827
End Site
24823365
Strand
+
Assembly
GRCh38
Biotype
lncRNA
Also known as
NCRNA00198
Summary
This gene is located in the Prader-Willi syndrome (PWS) region of chromosome 15, which is known to undergo imprinting. The transcript is believed to be non-coding. It is bi-allelically expressed in testis and kidney, but mono-allelically expressed from the paternal allele in brain. This gene is poly-adenylated and is known to undergo alternative splicing. Transcript variants may represent part of a complex imprinting center-SNURF-SNRPN transcription unit. The contribution of this gene to the PWS phenotype is unknown, but it has been suggested that it may play a role in establishing paternal imprinting in the PWS region, perhaps by maintaining the paternal allele in an open chromatin configuration. [provided by RefSeq, Sep 2009]