LncRNA:ENSG00000237036

Official Symbol

ZEB1-AS1  provided by HGNC

Official Full Name

ZEB1 antisense RNA 1 

Gene ID

220930 

Chromosome

chr10

Start Site

31206278

End Site

31320447

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

Summary

This locus produces long non-coding RNA that is transcribed from a shared bi-directional promoter with zinc finger E-box binding homeobox 1 (ZEB1). This transcript binds lysine methyltransferase 2A and promotes histone modifications that are thought to promote expression of ZEB1. Expression of this gene is correlated with tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017] 

M6ARegulator:ENSG00000122566

Official Symbol

HNRNPA2B1  provided by HGNC

Official Full Name

heterogeneous nuclear ribonucleoprotein A2/B1 

m6A Category

readers 

Gene ID

3181 

Chromosome

chr7 

Start Site

26173057 

End Site

26201529 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

HNRNPA2|HNRNPB1|HNRPA2|HNRPA2B1|HNRPB1|IBMPFD2|RNPA2|SNRPB1 

Summary

"This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]" 

Differentially expressed Detail
Symbol ZEB1-AS1  HNRNPA2B1 
Pvalue 6.2e-07  1.2e-01 
Log2FC -1.1e+00  1.9e-01 
Significant DOWN REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.51 
Correlation FDR 1.9e-12