LncRNA:ENSG00000268388

Official Symbol

FENDRR  provided by HGNC

Official Full Name

FOXF1 adjacent non-coding developmental regulatory RNA 

Gene ID

400550 

Chromosome

chr16

Start Site

86474529

End Site

86509099

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

FOXF1-AS1|FOXF1AS1|TCONS_00024240|lincFOXF1|onco-lncRNA-21 

Summary

This gene produces a spliced long non-coding RNA transcribed bidirectionally with FOXF1 on the opposite strand. A similar gene in mouse is essential for normal development of the heart and body wall. The encoded transcript is thought to act by binding to polycomb repressive complex 2 (PRC2) and/or TrxG/MLL complexes to promote the methylation of the promoters of target genes, thus reducing their expression. It has been suggested that this transcript may play a role in the progression of gastric cancer. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015] 

M6ARegulator:ENSG00000185728

Official Symbol

YTHDF3  provided by HGNC

Official Full Name

YTH N6-methyladenosine RNA binding protein 3 

m6A Category

readers 

Gene ID

253943 

Chromosome

chr8 

Start Site

63168553 

End Site

63212786 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

DF3 

Summary

"This gene encodes a member of the YTH (YT521-B homology) domain protein family. The YTH domain is common in eukaryotes, is often found in the middle of the protein sequence, and may function in binding to RNA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]" 

Differentially expressed Detail
Symbol FENDRR  YTHDF3 
Pvalue 9.0e-02  1.2e-03 
Log2FC -1.3e+00  -6.5e-01 
Significant NOT SIGNIFICANT  NOT SIGNIFICANT 
Correlation coefficient 0.32 
Correlation FDR 3.5e-05