LncRNA:ENSG00000245526

Official Symbol

LINC00461  provided by HGNC

Official Full Name

long intergenic non-protein coding RNA 461 

Gene ID

645323 

Chromosome

chr5

Start Site

88507546

End Site

88691057

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

ECONEXIN|EyeLinc1|NDIME|VISC 

Summary

This is an evolutionarily conserved gene that produces alternatively spliced long non-coding RNAs that may be expressed predominantly in the brain and visual cortex. These transcripts may be involved in tumorigenesis, as depletion by siRNA suppressed glioma cell division. Transcripts may also bind to and regulate the activity of miR-411-5p and argonaut 2, thereby altering the expression of genes involved in tumor growth. [provided by RefSeq, Nov 2017] 

M6ARegulator:ENSG00000146457

Official Symbol

WTAP  provided by HGNC

Official Full Name

WT1 associated protein 

m6A Category

writers 

Gene ID

9589 

Chromosome

chr6 

Start Site

159725585 

End Site

159756319 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

Mum2 

Summary

"The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012]" 

Differentially expressed Detail
Symbol LINC00461  WTAP 
Pvalue 7.8e-01  2.6e-03 
Log2FC 1.9e-01  -5.3e-01 
Significant NOT SIGNIFICANT  NOT SIGNIFICANT 
Correlation coefficient 0.35 
Correlation FDR 7.0e-06