Official Symbol

LINC00461  provided by HGNC

Official Full Name

long intergenic non-protein coding RNA 461 

Gene ID

645323 

Chromosome

chr5

Start Site

88507546

End Site

88691057

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

ECONEXIN|EyeLinc1|NDIME|VISC 

Summary

This is an evolutionarily conserved gene that produces alternatively spliced long non-coding RNAs that may be expressed predominantly in the brain and visual cortex. These transcripts may be involved in tumorigenesis, as depletion by siRNA suppressed glioma cell division. Transcripts may also bind to and regulate the activity of miR-411-5p and argonaut 2, thereby altering the expression of genes involved in tumor growth. [provided by RefSeq, Nov 2017] 

Official Symbol

FTO  provided by HGNC

Official Full Name

FTO alpha-ketoglutarate dependent dioxygenase 

m6A Category

erasers 

Gene ID

79068 

Chromosome

chr16 

Start Site

53701692 

End Site

54158512 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

ALKBH9|BMIQ14|GDFD 

Summary

"This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]"