Official Symbol

PVT1  provided by HGNC

Official Full Name

Pvt1 oncogene 

Gene ID

5820 

Chromosome

chr8

Start Site

127794526

End Site

128187101

Strand

+ 

Assembly

GRCh38

Biotype

lncRNA

Also known as

LINC00079|MIR1204HG|NCRNA00079|onco-lncRNA-100 

Summary

This gene represents a long non-coding RNA locus that has been identified as a candidate oncogene. Increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Allelic variants of this gene are also associated with end-stage renal disease attributed to type 1 diabetes. Consistent with its association with various types of cancer, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. [provided by RefSeq, Sep 2015] 

Official Symbol

RBMX  provided by HGNC

Official Full Name

RNA binding motif protein X-linked 

m6A Category

readers 

Gene ID

27316 

Chromosome

chrX 

Start Site

136848004 

End Site

136880764 

Strand

- 

Assembly

GRCh38

Biotype

protein coding 

Also known as

HNRNPG|HNRPG|MRXS11|RBMXP1|RBMXRT|RNMX|hnRNP-G 

Summary

"This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns. [provided by RefSeq, Sep 2009]"