LncRNA:ENSG00000099869

Official Symbol

IGF2-AS  provided by HGNC

Official Full Name

IGF2 antisense RNA 

Gene ID

51214 

Chromosome

chr11

Start Site

2140501

End Site

2148666

Strand

Assembly

GRCh38

Biotype

lncRNA

Also known as

IGF2-AS1|IGF2AS|PEG8 

Summary

This gene is expressed in antisense to the insulin-like growth factor 2 (IGF2) gene and is imprinted and paternally expressed. It is thought to be non-coding because the putative protein is not conserved and translation is predicted to trigger nonsense mediated decay (NMD). Transcripts from this gene are produced in tumors and may function to suppress cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015] 

M6ARegulator:ENSG00000159217

Official Symbol

IGF2BP1  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 1 

m6A Category

readers 

Gene ID

10642 

Chromosome

chr17 

Start Site

48997385 

End Site

49056145 

Strand

Assembly

GRCh38

Biotype

protein coding 

Also known as

CRD-BP|CRDBP|IMP-1|IMP1|VICKZ1|ZBP1 

Summary

"This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]" 

Differentially expressed Detail
Symbol IGF2-AS  IGF2BP1 
Pvalue 2.3e-05  7.0e-02 
Log2FC 1.8e+00  6.1e-01 
Significant UP REGULATED  NOT SIGNIFICANT 
Correlation coefficient 0.33 
Correlation FDR 2.2e-07