Official Symbol

XIST  provided by HGNC

Official Full Name

X inactive specific transcript 

Gene ID

7503 

Chromosome

chrX

Start Site

73820649

End Site

73852723

Strand

- 

Assembly

GRCh38

Biotype

lncRNA

Also known as

DXS1089|DXS399E|LINC00001|NCRNA00001|SXI1|swd66 

Summary

X inactivation is an early developmental process in mammalian females that transcriptionally silences one of the pair of X chromosomes, thus providing dosage equivalence between males and females. The process is regulated by several factors, including a region of chromosome X called the X inactivation center (XIC). The XIC comprises several non-coding and protein-coding genes, and this gene was the first non-coding gene identified within the XIC. This gene is expressed exclusively from the XIC of the inactive X chromosome, and is essential for the initiation and spread of X-inactivation. The transcript is a spliced RNA. Alternatively spliced transcript variants have been identified, but their full length sequences have not been determined. Mutations in the XIST promoter cause familial skewed X inactivation. [provided by RefSeq, Apr 2012] 

Official Symbol

IGF2BP1  provided by HGNC

Official Full Name

insulin like growth factor 2 mRNA binding protein 1 

m6A Category

readers 

Gene ID

10642 

Chromosome

chr17 

Start Site

48997385 

End Site

49056145 

Strand

+ 

Assembly

GRCh38

Biotype

protein coding 

Also known as

CRD-BP|CRDBP|IMP-1|IMP1|VICKZ1|ZBP1 

Summary

"This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]"